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Biography
William Clayton may refer to:
William Clayton (Liverpool MP) (died 1715), Member of Parliament for Liverpool, 1698–1708
Sir William Clayton, 1st Baronet (died 1744), Member of Parliament for Bletchingley, 1715–1744
William Clayton, 1st Baron Sundon (1671–1752), MP for Woodstock, St Albans, Westminster, Plympton Erle and St Mawes
William Clayton (died 1783) (c. 1718–1783), Member of Parliament for Bletchingley, 1745–1761, and Great Marlow, 1761–1783
Sir William Clayton, 4th Baronet (1762–1834), Member of Parliament for Great Marlow, 1783–1790
Sir William Clayton, 5th Baronet (1786–1866), Member of Parliament for Great Marlow, 1832–1842
William Clayton (Mormon) (1814–1879), Mormon pioneer
Sir William Clayton (architect) (1823–1877), prominent New Zealand architect
William C. Clayton (1831–1915), American educator, lawyer, politician, and businessperson
William F. Clayton (born 1923), US politician
William L. Clayton (1880–1966), US assistant secretary of state for economic affairs
William Clayton (publisher), publisher of Astounding Stories
William Clayton (Governor) (1632–1689), acting Governor of the Pennsylvania Colony, 1684–1685
William Wirt Clayton (1812–1885), judge, director and tax collector in Atlanta, Georgia
William M. Clayton, US politician, mayor of Denver, Colorado, 1868–1869