Quick Facts
CancerBiography
Iva Marija Tolić (born 24 June 1974) is a Croatian Biophysicist, known for her work on the microtubule cytoskeleton and associated motor proteins. She is currently Senior Research Group Leader and Professor of Biology at the Ruđer Bošković Institute in Zagreb, Croatia.
Education
Tolić completed her Diploma in Molecular Biology from the University of Zagreb, Croatia in 1996 and her Graduate Studies in Molecular Biology in the group of Prof. Nenad Trinajstić, Ruđer Bošković Institute and University of Zagreb, Croatia in 1999. Between 1999 and 2001, she completed part of her PhD work with Prof. Ning Wang, Harvard School of Public Health, Boston, United States and was awarded her doctorate in Biology in 2002 by the University of Zagreb, Croatia.
Career
Upon obtaining her doctorate, Tolić did her first Post-doctoral training between 2001 and 2002 at the Niels Bohr Institute, Copenhagen, Denmark working with Prof. Lene Oddershede and Prof. Kirstine Berg-Sorensen on the microrheology of cells. She then joined the European Laboratory for Non-Linear Spectroscopy, Florence, Italy for post-doctoral research with Prof. Francesco Pavone, working on lymphocyte movement and laser microsurgery on the mitotic spindle. Following her Post-doctoral training, Tolić was appointed as Research Group Leader (W1, equivalent to Assistant Professor) at the Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany in 2005 and was promoted to Senior Research Group Leader (W2, equivalent to Associate Professor) in 2010. In 2014, she moved to the Ruđer Bošković Institute, Zagreb, Croatia, being appointed as Senior Research Group Leader and Professor of Biology. Under her mentorship, 6 PhDs, 4 master's degrees and 6 diplomas have been awarded.
Research
As independent investigator, Tolić has carried out pioneering research in the field of cell biology pertaining to the microtubule cytoskeleton and associated motor proteins, discovering: (i) a novel mechanism of kinetochore capture during mitosis by pivoting of astral microtubules around the spindle pole, (ii) a mechanism of regulation of the motor protein cytoplasmic dynein by attachment to its anchor protein in fission yeast and most recently, (iii) 'Bridging fibers' that are non-kinetochore microtubules connecting sister k-fibers and thereby balancing forces in the spindle
In addition, her research has demonstrated that fission yeast does not undergo replicative aging, contrary to existing theories on aging.
Personal life
Tolić's parents are the journalist and diplomat Benjamin Tolić and academic Dubravka Oraić-Tolić. She married Nenad Brgić in 2014 and she is the mother of two children.
Awards and Achievements
- Croatian Women of Influence Award, 2016.
- Special award of the Ruđer Bošković Institute for outstanding contribution to the scientific excellence and international recognition of the institute, 2015.
- European Biophysical Societies Association Young Investigators' Medal and Prize, 2015.
- 5000th Grantee of the European Research Council, 2015.
- MRAK award for creativity in science awarded for the collaboration with the Ruđer Bošković Institute.
- Order of Danica Hrvatska for science, outstanding contributions to science and its promotion in the Republic of Croatia and the world, 2014
- Investigator of the Year, European Life Science Award, 2014.
- Featured on Cell "40 under 40", 2014.
Membership in Professional Associations and Societies
Tolić is a member of the Croatian Biophysical Society, the Croatian Society of Biochemistry and Molecular Biology and the Croatian Microscopy Society. In addition, she is Member of the Scientific Advisory Board of the journal Science Matters.
Publications
Tolić has 65 publications in international peer-reviewed journals to her credit, with a total citation count of ~3500 and an h-index of 26. Her complete list of publications can be found on her website.
Media Coverage
Tolić and her research have been covered by several international and Croatian media outlets: Gloria, Croatia Airlines, Bild and Voice of Croatia, to name a few.