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Ieuan Hughes is a paediatric endocrinologist and a professor emeritus of paediatrics at the University of Cambridge. He was elected a Fellow of the Academy of Medical Sciences in 1998. In 2014 he was awarded the James Spence Medal, the highest honour given by the Royal College of Paediatrics and Child Health.

Hughes was a professor of paediatrics at the University of Cambridge, and the head of the School of Clinical Medicine's Department of Paediatrics for 23 years before retiring as a professor emeritus. Throughout his career in paediatric endocrinology, he specialised in disorders of sex development (DSD); he created a comprehensive database of DSD cases and established international consensus-based guidelines for the management of these cases. He also founded and chaired the Clinical Committee of the British Society for Paediatric Endocrinology and Diabetes and published over 230 original journal articles.

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