Caroline Moore

Caroline M. Moore is a Professor of Urology at University College London. She works in the diagnosis and treatment of prostate cancer. She was the first woman to be made a Professor of Urology in the United Kingdom.

Moore was born in Chester, and moved to Wombourne at the age of five. She studied at St Edmunds Catholic College. She studied medicine at St George's, University of London, and graduated in 1997. She completed her medical training in London, before starting her MD on photodynamic therapy in 2002.

Moore was awarded a research fellowship from the Royal College of Surgeons. She is based in the Department of Urology at University College London Hospital (UCLH) and the Division of Surgical & Interventional Sciences at University College London (UCL). UCL/UCLH has a leading diagnostic research programme for prostate cancer, including urologists, radiologists, engineers and computer medical imaging specialists. She has a variety of research interests, including the use of magnetic resonance imaging (MRI) and non-traditional follow-up methods. Her research has been supported by the Movember Foundation.

Moore has used MRI to identify prostate cancer and target biopsies. Moore started using MRI to detect prostate cancer in men who would not need treatment, and found that if biopsies were performed before MRI scans the images were blurred.In October 2012 she established a committee on Standards in Reporting in MRI-targeted biopsy (START). The recommendations included reporting histologic results of standard cores using Gleason scores and maximum core cancer length, as well as reporting the recruitment criteria, radiologist experience and population biopsy status of a particular trial. She has worked on a combination of multi-parametric MRI and cognitive fusion transperineal biopsy, which can reduce the time taken diagnose and treat diseases. She has found that using MRI can reduce the need for biopsies by 28%. Her MRI protocols have been rolled out across the United Kingdom.

Moore has developed electronic psychometric patient-reported outcome measures to monitor men who have had radical prostatectomy. Men who have this surgery can suffer from urinary leakage and difficulties with erections. The survey allows researchers to track their progress and share information with their surgical teams. Moore has recently been among a group of researchers spread across six hospitals who have been investigating high-intensity focused ultrasound (HIFU) as a treatment for prostate cancer. Five years after treatment with HIFU the cancer survival rate is 100%, the same as for the more traditional methods of surgery and radiotherapy, but with fewer side-effects.

She has been Head of Urology at University College London, within the Division of Surgical and Interventional Sciences since 2018. She was recently senior author on the Prostate Evaluation for Clinically Important Disease: Sampling Using Image Guidance or Not? (PRECISION) study comparing standard prostate biopsy and MRI-targeted biopsy. The paper was awarded The BMJ "UK Research Paper" of the year. In 2019 Moore was the first woman in the United Kingdom to be made a Professor of Urology. She serves on the board of the European Association of Urology Research Foundation.

She has served as a science consultant for the science comic Surgeon X.