Yaariv Khaykin

Yaariv Khaykin is a Canadian cardiologist and a clinical researcher in the area of electrophysiology. He is the director of the Newmarket Electrophysiology Research Group at the Southlake Regional Health Centre. He has published research into complex ablation and pioneered cardiac ablation methods.

Khaykin attended the University of Toronto, completing his medical degree in 1996. He later did residency in internal medicine as well as a fellowship in cardiovascular medicine at the University of Toronto. He also trained in electrophysiology at the Cleveland Clinic.

Khaykin joined Southlake Regional Health Center in 2004 as an electrophysiologist. He started a complex ablation program there, developing it into one of the most successful ablation programs inCanada, performing the second highest number of procedures each year.

Khaykin currently directs the Newmarket Electrophysiology Research Group at Southlake. Khaykin co-founded the Canadian Atrial Fibrillation and the Complex Ablation Alliance steering committees. As a member of the group he has contributed to the development of national registries for atrial fibrillation and ventricular tachycardia. Khaykin was also a member of the Arrhythmia Management Committee of the Cardiovascular Care Network, as well as the Publication Committee for the Institute for Clinical Evaluative Sciences' Implantable cardioverter-defibrillator registry, Ontario's version of the National Cardiovascular Data Registry.

As a cardiologist Khaykin specializes in the implantation of pacemakers, implantable cardioverter-defibrillator (ICDs), cardiac resynchronization therapy (CRT), laser lead extraction and ablation of atrial fibrillation and ventricular tachycardia, among other cardiac services.

Khaykin has been involved in collaborative research into a variety of themes related to cardiovascular health. He has researched into atrial fibrillation and complex ablation at the Southlake Regional Health Centre. Since 2004 he has been conducting clinical research into antiarrhythmic agents, cardiac rhythm management devices, coronary angiography, electrophysiology, ablation procedures and imaging and mapping technologies. His research has compared various methods to treat atrial fibrillation and ventricular tachycardia using 3D, ultrasound guidance, radiofrequency and other techniques.

Khaykin and a fellow electrophysiologist, Atul Verma, were the first cardiologists in Canada to use "a revolutionary technology that makes it easier to connect with human tissue when guiding catheters into the heart to treat problem areas, reducing patient risk while improving outcomes". The technology takes "precise electrical measurements at the tip of a cardiac catheter, providing cardiac specialists with both numbers and a visual display so they know when good tip-to-tissue contact is made".

Khaykin was also the first Canadian doctor to use the Medtronic Ablation Frontiers Cardiac Ablation System, radiofrequency ablation method applied to the treatment of atrial fibrillation.

Khaykin, in collaboration with other researchers, has published several peer-reviewed articles and given a number of presentations in the field of cardiac electrophysiology. His publications include the following:

• with Matthew R. Reynolds et al. (January 2014). "Cost-effectiveness of cryoballoon ablation for the management of paroxysmal atrial fibrillation". Europace. 16 (5): 652–659. doi:10.1093/europace/eut380. PMID 24390386.CS1 maint: uses authors parameter (link)
• with Zachary WM. Laksman et al. (January 2014). "Higher Mortality Risk Among Patients With Delayed Follow-Up After Implantable Cardioverter Defibrillator Procedures". The Canadian Journal of Cardiology.CS1 maint: uses authors parameter (link)
• with Stephen B. Wilton et al. (January 2014). "Left Ventricular Lead Position and Outcomes in the Resynchronization-Defibrillation for Ambulatory Heart Failure Trial (RAFT)". The Canadian Journal of Cardiology. 30 (4): 413–419. doi:10.1016/j.cjca.2013.10.009. PMID 24561009.CS1 maint: uses authors parameter (link)
• with Roberto Mantovan et al. (August 2013). "Relationship of Quality of Life With Procedural Success of Atrial Fibrillation (AF) Ablation and Postablation AF Burden: Substudy of the STAR AF Randomized Trial". The Canadian Journal of Cardiology.CS1 maint: uses authors parameter (link)
• with Derek Yung et al. (June 2013). "Survival after implantable cardioverter-defibrillator implantation in the elderly" (PDF). Circulation. 127 (24): 2383–92. doi:10.1161/circulationaha.113.001442. PMID 23775193.CS1 maint: uses authors parameter (link)
• Khaykin, Yaariv; Shamiss, Yana (2011). "Cost of AF Ablation: Where Do We Stand?". Cardiology Research and Practice. 2011: 1–6. doi:10.4061/2011/589781. PMC 3051175. PMID 21403880.
• Yaariv Khaykin et al. (2009). "A Randomized Controlled Trial of the Efficacy and Safety of Electroanatomic Circumferential Pulmonary Vein Ablation Supplemented by Ablation of Complex Fractionated Atrial Electrograms Versus Potential-Guided Pulmonary Vein Antrum Isolation Guided by Intracardiac Ultrasound". Circulation: Arrhythmia and Electrophysiology. 2 (5): 481–487. doi:10.1161/circep.109.848978. PMID 19843915.CS1 maint: uses authors parameter (link)
• Yaariv Khaykin et al. (2009). "Cost Comparison of Ablation Versus Antiarrhythmic Drugs As First-Line Therapy for Atrial Fibrillation: An Economic Evaluation of the RAAFT Pilot Study". Journal of Cardiovascular Electrophysiology. 20 (1): 7–12. doi:10.1111/j.1540-8167.2008.01303.x. PMID 18803564.CS1 maint: uses authors parameter (link)
• Yaariv Khaykin et al. (2008). "Real-time integration of 2D intracardiac echocardiography and 3D electroanatomical mapping to guide ventricular tachycardia ablation". Heart Rhythm. 5 (10): 1396–1402. doi:10.1016/j.hrthm.2008.06.025.CS1 maint: uses authors parameter (link)
• Yaariv Khaykin et al. (September 2007). "Cost Comparison of Catheter Ablation and Medical Therapy in Atrial Fibrillation". Journal of Cardiovascular Electrophysiology. 18 (9): 907–913. doi:10.1111/j.1540-8167.2007.00902.x.CS1 maint: uses authors parameter (link)
• Khaykin, Yaariv; Saad, Eduardo B.; Wilkoff, Bruce L. (2003). "Pacing in heart failure: the benefit of resynchronization". Cleveland Clinic Journal of Medicine. 70 (10): 841–865. doi:10.3949/ccjm.70.10.841.
• with Derek V. Exner et al. "Risk Estimation Following Infarction Noninvasive Evaluation - ICD Efficacy". University of Calgary, Alberta Innovation and Science, Medtronic, GE Healthcare. CS1 maint: uses authors parameter (link)

• Khaykin, along with Gal Hayam, Limor Elran and Aharon Turgeman, invented and holds a patent for an Automated analysis of complex fractionated electrograms, a "method for mapping abnormal electrical activity" in the heart. The method is able to identify and analyze complex fractionated electrograms (CFEs).