Srpuhi Mayrabed Nshan Kalfayan (Armenian: Սրբուհի Մայրապետ Նշան Գալֆաեան) (Born February 17, 1822 in Kartal, Istanbul; † July 4, 1889 in Hasköy, Istanbul) was an Armenian nun and founder of the 'Order of Kalfayan', plus a school and an orphanage for girls in Constantinople.
Kalfayan vowed to become a nun at the age of 12 when she lost her father, and she achieved it in 1840.
Kalfayan founded both the 'Order of Kalfayan' and, in 1850, a school for girls which still stands today (Though now it accepts boys as well).
In 1865 she mobilized financial support for the victims of a cholera epidemic and on 1 January 1866 she opened an orphanage for girls in Hasköy, Constantinople.
Death and commemoration
Kalyfan died on 4 July 1889.
Her name is commemorated in the 'Kalfayan Elementary School'.