|Birth||20 November 1563 (Stuttgart)|
|Death||21 July 1590 (Vacha)|
Sophie of Württemberg (20 November 1563 - 21 July 1590), was a German noblewoman member of the House of Württemberg and by marriage Duchess of Saxe-Weimar.
Born in Stuttgart, she was the youngest of twelve children born from the marriage of Christoph, Duke of Württemberg and Anna Maria of Brandenburg-Ansbach. From her eleven older siblings, nine survive adulthood: Eberhard, Hereditary Prince of Württemberg, Hedwig (by marriage Landgravine of Hesse-Marburg), Elisabeth (by her two marriages Countess of Henneberg-Schleusingen and Countess Palatine of Veldenz-Lauterecken), Sabine (by marriage Landgravine of Hesse-Kassel), Emilie (by marriage Countess Palatine of Simmern-Sponheim), Eleonore (by her two marriages Princess of Anhalt and Landgravine of Hesse-Darmstadt), Louis III, Duke of Württemberg, Dorothea Maria (by marriage Countess Palatine of Sulzbach) and Anna (by her two marriages Duchess of Oława and Legnica).
In Weimar on 5 May 1583 Sophie married Frederick William I, Duke of Saxe-Weimar. They had six children, of whom only two survive adulthood:
- Dorothea Marie (Weimar, 8 May 1584 – Weimar, 9 September 1586).
- John William, Hereditary Prince of Saxe-Weimar (Weimar, 30 June 1585 – Weimar, 23 January 1587).
- Frederick (Weimar, 26 September 1586 – Weimar, 19 January 1587).
- Dorothea Sophia (Weimar, 19 December 1587 – Weimar, 10 February 1645), Princess-Abbess of Quedlinburg (1618).
- Anna Marie (Weimar, 31 March 1589 – Dresden, 15 December 1626).
- stillborn son (Vacha, 21 July 1590).
Sophie died in Vacha aged 26, following complications of her last childbirth. She was buried in the Stadtkirche St.Peter und Paul, Weimar.