Sir William Domville, 1st Baronet (26 December 1742 – 8 February 1833) was Lord Mayor of London for 1813–14.
He was born in St Albans, the son of Charles Domville of London and was a descendant of William Domville, elder brother of Gilbert Domvile, ancestor of the Domvile baronets of Templeogue. He set up in business as a bookseller in London before returning to live in St Albans.
He was Master of the Worshipful Company of Stationers and Newspaper Makers, a Sheriff of London for 1804–05 and Lord Mayor of London for 1813–14. In 1805 he was elected an Alderman of Queenhithe Ward and made a baronet in 1814.
He died 8 February 1833 and was buried in St Albans Abbey. He had married Sally, the daughter of Archibald Finney and had two sons and five daughters.