Rudi Pauwels (born 1960) is a Belgian pharmacologist. He studied pharmaceutical sciences at the Catholic University of Leuven, Belgium, and obtained a PhD with a dissertation on Development of New Anti-HIV Agents.
He did research on virology at the Rega Institute for Medical Research . In 1994 he founded the Belgian biotech company Tibotec, together with his wife Carine Claeys, and in 1995 he co-founded Virco. At Tibotec he continued his work on HIV. In 1999, he was elected as board member of the Flemish Institute for Biotechnology (VIB).
Rudi Pauwels is also the co-founder, director and CEO of a molecular diagnostic company, Biocartis SA, based in Parc Scientifique EPFL, Lausanne, Switzerland.
Pauwels is the father of actress Eline Powell.