Dr. Richard Wayne (April 4, 1804 – June 27, 1858) served as mayor of Savannah, Georgia for four terms: 1844 - 1845, 1848–1851, 1852–1853 and 1857 - 1858. He died while in office.
Wayne was the first mayor of Savannah elected by its citizens. Prior to his election, mayors were appointed by the city aldermen. He is buried in Savannah's Laurel Grove Cemetery.