Ole Tøpholm (born 9 October 1977 in Silkeborg) is a Danish radio host.
Tøpholm graduated in 2002 at Journalisthøjskolen with a journalism degree. Since 2000 he has been working for the Danish broadcaster Danmarks Radio as a reporter on Radioavisen and he is currently the morning news presenter for DR P3.
Since 2011, Tøpholm has been the regular Danish Commentator at the Eurovision Song Contest. A devoted fan since childhood, he was chairman of the Danish Eurovision fan club. He published a book Dansk Melodi Grand Prix – De største øjeblikke, devoted to The Dansk Melodi Grand Prix.