Nikita Khlystov (born July 23, 1993) is a Russian professional ice hockey defenceman. He is currently playing with Metallurg Magnitogorsk in the Kontinental Hockey League (KHL). He has previously played three stints with Traktor Chelyabinsk in the KHL.
Khlystov made his Kontinental Hockey League debut playing with Traktor Chelyabinsk during the 2013–14 KHL season.
On 1 May 2020, Khlystov joined his sixth KHL club, after he was traded by Severstal Cherepovets in exchange for financial compensation.