Nat Polen (June 14, 1914 — May 3, 1981) was an American actor. He is known for his long-running character roles playing physicians on ABC and CBS soap operas.
Polen played Dr. Doug Cassen on As the World Turns for over 10 years, from 1956 until 1967. He later became recognized for playing Dr. Jim Craig on One Life to Live from 1969 until shortly before his death from pancreatic cancer in 1981. He was also a film actor, playing Lt. Reilly in the 1972 film Across 110th Street. Other credits include appearing in 37 episodes of CBS Radio Mystery Theatre.