Mangle Minthorne Tompkins (December 26, 1807 – June 5, 1881 New York City) was an American politician from New York.
He was the son of Daniel D. Tompkins (1774–1825) and Hannah (Minthorne) Tompkins (1781–1829). He was born while his father was Governor of New York. He graduated from Union College in 1827.
He was a Jacksonian member of the New York State Assembly (New York Co.) in 1833 and 1834.
He was a Democratic member of the New York State Senate (1st D.) in 1840 and 1841. He resigned his seat on March 8, 1841.
In November 1852 he ran on the Free Democratic ticket for Governor of New York, but was defeated by Democrat Horatio Seymour.
He was for some time a port warden of the Port of New York, and about 1869 was President of the Board of Port Wardens.
Assemblyman Jonathan G. Tompkins (1736–1823) was his grandfather; Congressman Caleb Tompkins (1759–1846) was his uncle.