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Margrethe Marie Thomasine Numsen, née Ingenhaef(f) (8 March 1705 -8 October 1776), was a politically active Danish courtier.
She was the daughter of general major noble Johan Peter Ingenhaeff and married in 1725 to general noble Michael Numsen. She was given the Ordre de l'Union Parfaite 1753. After the death of her spouse in 1757, she became a central figure in court life, attributed political influence and often criticized. In 1772-1773, she was the head of the court of the crown prince, the future Frederick VI of Denmark, who reportedly liked her very much and called her Mutter. She lost her position and was forced to leave court in September 1773, after having participated in a plot directed against the rule of the queen dowager Juliana Maria of Brunswick-Wolfenbüttel and her party.