Jan Mandijn or Jan Mandyn (c.1500, Haarlem –c.1560, Antwerp) was a Dutch Renaissance painter, who worked in Antwerp after 1530.
Mandijn trained in Haarlem. He moved to Antwerp in 1530.
Only one signed work of Mandijn survives, the Temptation of Saint Anthony (Frans Hals Museum in Haarlem). It is similar in style to Hieronymus Bosch and that is why he is called a follower of Bosch. This is confirmed by the early biographer Karel van Mander who wrote that Mandijn was good at painting spooky and funny scenes like Hieronymus Bosch. The 'Temptation' is inspired by Bosch’s work, but Mandijn's style was freer and looser and the colours and fantastic creatures are less harmonious. As a result the whole is less powerful than Bosch. Mandijn's paintings incorporate the elements typical of Bosch such as hybrid demons composed of various parts of insects, amphibians, reptiles and birds.
The stylistic features of Mandijn's style have been identified in a series of Antwerp ‘devil pictures’ that have been attributed to him, such as the Temptation of Saint Christopher (Alte Pinakothek in Munich).