Hendrik Streeck (born 7 August 1977 in Göttingen) is a German HIV researcher, epidemiologist and clinical trialist. He is professor for medical biology and the director of the Institute for HIV Research at the University of Duisburg-Essen.
Hendrik Streeck studied medicine at the Charite University, Berlin and obtained his PhD from the University of Bonn, which he performed part-time at the Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School. After his graduation he started to work as a postdoctoral fellow at the Ragon Institute of MGH, MIT and Harvard. In 2009 he was promoted to Instructor in Medicine and in 2011 to Assistant Professor at Harvard Medical School. In September 2012 he was recruited to the United States Military HIV Research Program, Bethesda, where he became the Chief of the Cellular Immunology Section as well as Assistant Professor at the Uniformed Services University of Health Sciences and adjunct faculty of the Bloomberg School of Public Health, Johns Hopkins University. In 2015 he became the Chair for Medical Biology at the University Duisburg-Essen and founded the Institute for HIV Research in the same year, though he still maintains the status of "visiting scientist" with the US Military HIV Research Program. In 2018 he was appointed to the advisory board of the German AIDS Foundation (Deutsche AIDS Stiftung).
Under his direction the Institute for HIV Research works on several prevention methods against HIV including the development and feasibility of HIV vaccines as well as Pre-exposure prophylaxis (PrEP). A particular focus for HIV vaccine development is to understand how T follicular helper (Tfh) cells can drive protective antibody responses during the germinal center reaction. Further research areas of the institute include understanding why some co-morbidities, such as cancer or cardiovascular diseases, are more prone to develop in chronic HIV infection and whether strategies can be developed to suppress HIV viral loads in the absence of antiretroviral therapy. Some of these studies are being performed in Maputo, Mozambique, where he leads a PhD sandwich program with the Instituto Nacionale de Saude to train and retain young physician scientists. Besides HIV, Hendrik Streeck actively investigates the epidemiology, novel prevention and treatment options of other sexually transmitted infections (STI). Currently, he conducts the largest systematic study for STIs in Germany (BRAHMS study) which seeks to understand who is becoming infected with which STI.
In January 2019 the BRAHMS study was expanded to other European countries including France, Italy, Spain, Poland and Hungary under the name STIPnet study. In parallel, a European HIV & STI prevention network will be established He has been nominated as the co-chair of International AIDS conference IAS 2021 in Berlin.
- 2015 – 15 HIV Advocates to Watch in 2015
- 2014 – People Magazine “Sexiest Scientist” 2014
- 2011 – Young Investigator Award, Collaborative AIDS Vaccine Discovery (CAVD) Bill and Melinda Gates Foundation
- 2010 – Young Investigator Award, 17th CROI, San Francisco, CA
- 2009 – Biennial German AIDS Award (DAIG-Award)
- 2009 – New Investigator Award, AIDS Vaccine Conference, Paris, 2009
- 2009 – New Investigator Award, 16th CROI, Montreal, Canada
- 2008 – Young Investigator Award, World AIDS Conference, Mexico City,2008
- 2008 – New Investigator Award, AIDS Vaccine Conference, Cape Town,2008
- 2008 – NIH Scholarship 2008, HIV-Vaccine, Keystone, Banff, 2008
- 2008 – Young Investigator Award, 15th CROI,Boston, MA
- 2007 – Young Investigator Award, 14th CROI, Los Angeles, CA
- 2006 – Young Investigator Award, 13th CROI, Denver, CO
- 2006 – Young Investigator Award, World AIDS Conference, Toronto, 2006.
- 2005 – Young Investigator Award, HIV-Pathogenesis, Keystone, Banff, 2005
- American Society for Microbiology (ASM)
- American Association of Immunologists (AAI)
- German Association of University Professors (Deutscher Hochschulverband)
Several scientific journals require expert consultation on newly submitted researcher articles prior to publication. Dr. Streeck is an ad-hoc reviewer for the following journals:
- AIDS Research and Human Retroviruses
- BMC Immunology
- Clinical and Vaccine Immunology
- EMBO Molecular Medicine
- European Journal of Immunology
- Frontiers in Immunology
- HIV Medicine
- Journal of AIDS
- Journal of Clinical Investigations
- Journal of Infectious Diseases
- Journal of Immunology
- Journal of Virology
- Nature Medicine
- Nature Protocols
- PLoS One
- PLoS Pathogens
- Trends in Immunology
- Viral Immunology
- H. Streeck, G. Alter: "Immune Responses to Viral Infections." In: D. D. Richman, J. Whitley, F. G. Hayden: Clinical virology. 4. edition. ASM Press, 2016, ISBN 978-1-55581-942-2
- H. Streeck: Bug Attack (The Adventures of Damien the CD4 Cell & his Friends).Band 1, ISBN 1-5052-4534-6< . (children book, age 3–6 years, English)
- B. T. Schultz, A. F. Oster, F. Pissani, J. E. Teigler, G. Kranias, G. Alter, M. Marovich, M. A. Eller, U. Dittmer, M. L. Robb, J. H. Kim, N. L. Michael, D. Bolton, H. Streeck: "Circulating HIV-Specific Interleukin-21+CD4+ T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions." In: Immunity. 2016.
- F. Pissani, H. Streeck: "Emerging concepts on T follicular helper cell dynamics in HIV infection" In: Trends in Immunology. 35(6), Jun 2014, S. 278–286.
- S. Ranasinghe, S. Cutler, I. Davis, R. Lu, D. Z. Soghoian, Y. Qi, J. Sidney, G. Kranias, M. D. Flanders, M. Lindqvist, B. Kuhl, G. Alter, S. G. Deeks, B. D. Walker, X. Gao, A. Sette, M. Carrington, H. Streeck: "Association of HLA-DRB1-restricted CD4⁺T cell responses with HIV immune control." In: Nature Medicine . 19(7), Jul 2013, S. 930–933.
- M. Lindqvist, J. van Lunzen, D. Z. Soghoian, B. D. Kuhl, S. Ranasinghe, G. Kranias, M. D. Flanders, S. Cutler, N. Yudanin, M. I. Muller, I. Davis, D. Farber, P. Hartjen, F. Haag, G. Alter, J. Schulze zur Wiesch, H. Streeck: "Expansion of HIV-specific T follicular helper cells in chronic HIV infection" In: Journal of Clinical Investigation. 122(9), 4. Sep 2012, S. 3271–3280.
- M. F. Chevalier, B. Jülg, A. Pyo, M. Flanders, S. Ranasinghe, D. Z. Soghoian, D. S. Kwon, J. Rychert, J. Lian, M. I. Muller, S. Cutler, E. McAndrew, H. Jessen, F. Pereyra, E. S. Rosenberg, M. Altfeld, B. D. Walker, H. Streeck: "HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function." In: Journal of Virology. 85(2), Jan 2011, S. 733–741.
- H. Streeck, B. Li, A. F. Poon, A. Schneidewind, A. D. Gladden, K. A. Power, D. Daskalakis, S. Bazner, R. Zuniga, C. Brander, E. S. Rosenberg, S. D. Frost, M. Altfeld, T. M. Allen: "Immune-driven recombination and loss of control after HIV superinfection" In: Journal of Experimental Medicine. 205(8), 4. Aug 2008, S. 1789–1796.