|Intro||Landgravine of Hesse-Kassel|
|Birth||20 March 1691, Bad Elster, Vogtlandkreis, Saxony, Germany|
|Death||17 March 1743, Kassel, Kassel Government Region, Hesse, Germany (aged 52 years)|
Dorothea Wilhelmine of Saxe-Zeitz (20 March 1691, in Bad Elster – 17 March 1743, in Kassel) was a duchess of Saxe-Zeitz by birth and by marriage Landgravine of Hesse-Kassel.
Dorothea Wilhelmine was a daughter of the Duke Maurice William of Saxe-Zeitz (1664-1718) from his marriage to Marie Amalie (1670 - 1739), daughter of the Elector Frederick William I of Brandenburg. By 1710 all her siblings had died and so, after her father's death Dorothea Wilhelmine was the last surviving member of the house of Saxe-Zeitz.
She married on 27 September 1717 in Zeitz with Landgrave William VIII of Hesse-Kassel (1682-1760). Queen Caroline of Great Britain reported to the Duchess of Orleans, the Landgravine "was ugly and had a weird head".
Dorothea Wilhelmine became mentally ill and no longer appeared in public after 1725. The new first lady at court was the Landgrave's favorite Barbara Christine von Bernhold whom he made Countess Bernold of Eschau while Dorothea Wilhelmine was still alive.
From their marriage, Dorothea Wilhelmine had the following children:
- Charles (1718-1719)
- Frederick II (1720-1785), Landgrave of Hesse-Kassel
- married 1740 Princess Mary of Great Britain (1723-1772)
- Maria Amalia (1721-1744), she died while engaged to be married with Margrave Charles Frederick Albert of Brandenburg-Schwedt