|Birth||June 5, 1420|
|Death||September 17, 1462 (Spangenberg)|
Anna of Saxony (5 June 1420 – 17 September 1462, Spangenberg) was a princess of Saxony and by marriage landgravine of Hesse.
Anna was the eldest daughter of the elector Frederick I of Saxony (1370–1428) from his marriage to Catherine (1395–1442), daughter of Duke Henry I "the Wild" of Brunswick-Lüneburg.
Anna, with a dowry of 19,000 Rhenish gold florins, married on 8 September 1433 in Kassel Landgrave Louis I of Hesse. Their engagement had been announced on the occasion of the Inheritance Treaty between the two houses in 1431 in Rotenburg an der Fulda. Through this marriage, Louis increased his territory considerably. He received the Saxon properties of Eschwege and Sontra from Anna's brother Frederick II of Saxony. Frederick II also renounced his rights to Wanfried.
From her marriage to Louis, Anna had the following children:
- Louis II (1438–1471), Landgrave of Hesse
- married in 1454 Countess Mechthild of Württemberg (1438-1495)
- Henry III (1440–1483), Landgrave of Hesse-Marburg
- married Countess Anna of Katzenelnbogen (1443-1494)
- Hermann (1449–1508), 1480-1508 Archbishop of Cologne
- Elisabeth (1453–1489), known as the Beautiful
- married in 1464 Count John III of Nassau-Weilburg (1441-1480)
- Frederick (1458–1463)