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Alfred Jost

Alfred Jost

French endocrinologist
Alfred Jost
The basics

Quick Facts

Intro French endocrinologist
Was Scientist Biologist Professor Physician Endocrinologist
From France
Type Academia Biology Healthcare Science
Gender male
Birth 27 July 1916, Strasbourg, France
Death 3 February 1991, Paris, France (aged 74 years)
Star sign Leo
Peoplepill ID alfred-jost
The details (from wikipedia)

Biography

Alfred Jost (1916–1991) was a French endocrinologist, and an early researcher in the field of fetal endocrinology. He is known for his discovery of the Müllerian inhibitor, now called anti-Müllerian hormone (AMH) or Müllerian inhibiting substance (MIS). His research demonstrated how hormones affect the development of male and female sex characteristics.

Career

Jost was a professor at the University of Paris, and was head of the Department of Comparative Physiology there in 1972. Jost was known for applying surgical methods to fetal endocrinology. He also taught many pre-doctoral students.

Research

During the 1950s and 1960s Jost studied the mechanism of somatic sex differentiation; his research showed that male characteristics must be imposed on the fetus by the testicular hormones testosterone and AMH, and that in the absence or inactivity of these hormones, the fetus becomes phenotypically female.

Jost also studied testicular differentiation, in collaboration with Solange Magre. He was the first to show that testicular organization is heralded by the development of pre-Sertoli cells, which progressively surround germ cells to form seminiferous tubules.

Death

He died February 3, 1991 at age 75, having retired from the Collège de France, but still active as the Secrétaire Perpétuel of the French Academy of Sciences.

The contents of this page are sourced from Wikipedia article on 25 Apr 2020. The contents are available under the CC BY-SA 4.0 license.
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References
https://books.google.com/books?id=T4VOAQAAIAAJ&pg=PA168
https://books.google.com/books?id=hXz1BwAAQBAJ&pg=PA42
https://books.google.com/books?id=LM3DGsfHXCAC&pg=PA277
https://books.google.com/books?id=noRMAQAAIAAJ&pg=PA37
https://books.google.com/books?id=D6TnKbTRBJoC&pg=PA77
https://books.google.com/books?id=JlqcQ0WhU_kC&pg=PA490
https://books.google.com/books?id=YZ8_CwAAQBAJ&pg=PA903
https://books.google.com/books?id=ez-aBQAAQBAJ&pg=PA1
//doi.org/10.1159%2F000129690
//pubmed.ncbi.nlm.nih.gov/18577872
https://catalogue.bnf.fr/ark:/12148/cb119090241
https://data.bnf.fr/ark:/12148/cb119090241
http://isni.org/isni/0000000000012213
http://data.bibliotheken.nl/id/thes/p133817229
https://www.idref.fr/026940590
https://viaf.org/viaf/34458470
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