Marc A. Suchard

Marc Adam Suchard (born December 23, 1972 in California) is an American statistician. He is Professor in the Departments of Biomathematics and of Human Genetics in the David Geffen School of Medicine at UCLA and in the Department of Biostatistics in the UCLA Fielding School of Public Health at the University of California, Los Angeles. He was elected as a Fellow of the American Statistical Association in 2012, and he received the COPSS Presidents' Award in 2013.

• Suchard, M. A., Weiss, R. E., & Sinsheimer, J. S. (2001). Bayesian selection of continuous-time Markov chain evolutionary models. Molecular Biology and Evolution, 18(6), 1001-1013.

Ayres DL, Darling A, Zwickl DJ, Beerli P, Holder MT, Lewis PO, Huelsenbeck JP, Ronquist F, Swofford DL, Cummings MP, Rambaut A and Suchard MA. BEAGLE: an application programming interface and high-performance computing library for statistical phylogenetics. Systematic Biology, in press

Crawford FW, Suchard MA. Transition probabilities for general birth-death processes with applications in ecology, genetics and evolution. Journal of Mathematical Biology, in press.

Bielejec F, Rambaut A, Suchard MA, Lemey P. SPREAD: spatial phylogenetic reconstruction of evolutionary dynamics. Bioinformatics, in press.

Weiss RE, Jia J, Suchard MA. A Bayesian model for the common effects of multiple predictors on mixed outcomes. Interface Focus, in press.

Faria NR, Suchard MA, Abecasis A, Sousa JD, Ndembi N, Camacho RJ, Vandamme AM, Lemey P. Phylodynamics of the HIV-1 CRF02_AG clade in Cameroon. Infection, Genetics and Evolution, in press.

Edwards CJ, Suchard MA, Lemey P, Welch JJ, Barnes I, Fulton TL, Barnett R, O'Connell TC, Coxon P, Monaghan N, Valdiosera CE, Lorenzen ED, Willerslev E, Baryshnikov GF, Rambaut A, Thomas MG, Bradley DG, Shapiro B. Ancient hybridization and an Irish origin for the modern polar bear matriline. Current Biology, 21, 1251-1258, 2011.

Nelson MI, Lemey P, Tan Y, Vincent A, Lam TTY, Detmer S, Viboud C, Suchard MA, Rambaut A, Holmes EC, Gramer M. Spatial dynamics of human-origin H1 influenza A virus in North American swine. PLoS Pathogens, e1002077, 2011.

Zhou H, Lange K and Suchard MA. Graphical processing units and high-dimensional optimization . Statistical Science, 25, 311-324, 2010

Tom J, Sinsheimer JS and Suchard MA. Reuse, recycle, reweigh: combating influenza through efficient sequential Bayesian computation for massive data. Annals of Applied Statistics, 4, 1722-1748, 2010

Huelsenbeck JP, Alfaro ME, Suchard MA. Biologically-inspired phylogenetic models strongly outperform the no-common-mechanism model. Systematic Biology, 60, 225-232, 2011

Edo-Matas D, Lemey P, Tom JA, Serna-Bolea C, van den Blink AE van't Wout AB, Schuitemaker H, Suchard MA. Impact of CCR5delta32 host genetic background and disease progression on HIV-1 intra-host evolutionary processes: efficient hypothesis testing through hierarchical phylogenetic models. Molecular Biology and Evolution, 28, 1605-1616, 2011.

Gray RR, Tatem AJ, Johnson JA, Alexseyenko AV, Pybus OG, Suchard MA, Salemi M. Bayesian phylogenetics of bacterial genomes: inferring the pandemic spread of methicillin-resistant Staphylococcus aureus ST239. Molecular Biology and Evolution, 28, 1593-1603, 2011

Shapiro B, Ho SYW, Drummond AJ, Suchard MA, Pybus OG, Rambaut A. A Bayesian phylogenetic method to estimate unknown sequence ages. Molecular Biology and Evolution, 28, 879-887, 2011

Auguste AJ, Lemey P, Pybus OG, Suchard MA, Salas RA, Adesiyun AA, Barrett AD, Tesh RB, Weaver SC, Carrington CV. Yellow fever virus maintenance in Trinidad and its dispersal throughout the Americas. Journal of Virology, 84, 9967-9977, 2010

Talbi C, Lemey P, Suchard MA, Abdelatif E, Jalal N, Echevarria JE, Moron SV, Rambaut A, Campiz N, Tatem AJ, Holmes EC, Bourhy H. Phylodynamics and human-mediated dispersal of a zoonotic virus. PLoS Pathogens, 6, e1001166, 2010

Bloomquist EW, Lemey P, Suchard MA. Three roads diverged? Routes to phylogeographic inference. Trends in Ecology and Evolution, 25, 626-632, 2010

Drummond AJ and Suchard MA. Bayesian random local clocks, or one rate to rule them all. BMC Biology, 8, 114, 2010

Shi B, Kitchen CMR, Weiser B, Mayers D, Foley B, Kimdar K, Anastos K, Suchard MA, Parker M, Brunner C, Burger H. Evolution and recombination of genes encoding HIV-1 drug resistance and tropism during antiretroviral therapy. Virology, 404, 5-20, 2010

Lemey P, Rambaut A, Welch JJ and Suchard MA. Phylogeography takes a relaxed random walk in continuous space and time. Molecular Biology and Evolution, 27, 1877-1885

Firth C, Kitchen A, Shapiro B, Suchard MA, Holmes EC and Rambaut A. Using time-structured data to estimate evolutionary rates of double-stranded DNA viruses. Molecular Biology and Evolution, 27, 2038-2051, 2010

Suchard MA, Wang Q, Chan C, Frelinger J, Cron A and West M. Understanding GPU programming for statistical computation: studies in massively parallel massive mixtures. Journal of Computational and Graphical Statistics, 19, 418-438, 2010

Campos PF, Willerslev E, Sher A, Orlando L, Axelsson E, Tikhonov A, Aaris-Sorensen K, Greenwood A, Kahlke RD, Kosintsev P, Krakhmalnaya T, Kuznetsova T, Lemey P, MacPhee R, Norris CA, Shepherd K, Suchard MA, Zazula GD, Shapiro B, Gilbert MTP. Ancient DNA analyses exclude humans as the driving force behind late Pleistocene musk ox (Ovibos moschatus) population dynamics. Proceedings of the National Academy of Sciences, USA, 107, 5675-5680, 2010

Bennett SN, Drummond AJ, Kapan DD, Suchard MA, Muñoz-Jordán JL, Pybus OG, Holmes EC and Gubler DJ. Epidemic dynamics revealed in dengue evolution. Molecular Biology and Evolution, 27, 811-818, 2010

Bloomquist EW and Suchard MA. Unifying vertical and non-vertical evolution: a stochastic ARG-based framework. Systematic Biology, 59, 27 – 41, 2010

Lemey P, Rambaut A, Drummond AJ and Suchard MA. Bayesian phylogeography finds its roots. PLoS Computational Biology, 5, e1000520, 2009

Liang LJ, Weiss RE, Redelings B and Suchard MA. Improving phylogenetic analyses by incorporating additional information from genetic sequence databases. Bioinformatics, 25, 2530 – 2536, 2009

Suchard MA and Rambaut A. Many-core algorithms for statistical phylogenetics. Bioinformatics, 25, 1370-1376, 2009.

O'Brien JD, Minin VN and Suchard MA. Learning to count: robust estimates for labeled distances between molecular sequences. Molecular Biology and Evolution, 26, 801-814, 2009.

Drummond AJ and Suchard MA. Fully Bayesian tests of neutrality using genealogical summary statistics. BMC Evolutionary Biology, 9, 68, 2008.

McBride AJ, Cerqueira GM, Suchard MA, Moreira AN, Zuerner RL, Reis MG, Haake DA, Ko AI and Dellagostin OA. Sequence conservation of the leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospria spp. Infection, Genetics and Evolution, in press.

Bloomquist EW, Dorman KS and Suchard MA. Stepbrothers: inferring partially shared ancestries among recombinant viral sequences. Biostatistics, 10, 106-120, 2009.

Kitchen CMR, Marconi V, Kuritzkes D, Bloomquist EW, Deeks SG and Suchard MA. Two-way Bayesian hierarchical phylogenetic models: an application to the co-evolution of gp120 and gp41 during partial treatment interruptions of enfuvirtide. Computational Statistics and Data Analysis, 53, 766-775, 2009.

Minin VN and Suchard MA. Fast, accurate and simulation-free stochastic mapping. Philosophical Transactions of the Royal Society, Series B, 363, 3985-3995, 2008.

Alekseyenko A, Lee C and Suchard MA. Wagner and Dollo: a stochastic duet by composing two parsiminious solos. Systematic Biology, 57, 772-784, 2008.

O'Brien JD, She ZA and Suchard MA. Dating the time of viral subtype divergence. BMC Evolutionary Biology, 8, 172, 2008.

Minin VN, Bloomquist EW and Suchard MA. Smooth ride through a rough skyline: Bayesian coalescent-based inference of population dynamics. Molecular Biology and Evolution, 25, 1459-1471, 2008.

Ferreira MAR and Suchard MA. Bayesian analysis of elapsed times in continuous-time Markov chains. Canadian Journal of Statistics, 26, 355-368, 2008.

Suchard MA, Lange K and Sinsheimer JS. Efficiency of protein production from mRNA. Journal of Statistical Theory and Practice, 2, 173-182, 2008.

Wong KM, Suchard MA and Huelsenbeck JP. Alignment uncertainty and genomic analysis. Science, 319, 473-476, 2008.

Minin VN and Suchard MA. Counting labeled transitions in continuous-time Markov models of evolution. Journal of Mathematical Biology, 56, 391-412, 2008.

Su F, Lang J, Kumar A, Ng C, Hsieh B, Suchard MA, Reddy ST and Farias-Eisner R. Validation of candidate ovarian cancer biomarkers for early detection. Biomarkers Insight, 2, 367-375, 2007.

Stevenson B, Choy HA, Pinne M, Rotondi ML, Miller MC, DeMoll E, Kraiczy P, Colley AE, Creamer TP, Suchard MA, Brissttee CA, Verma A and Haake DA. Leptospira interrgans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. PLoS ONE, 2, e1188, 2007.

Stanczak CM, Chen Z, Nelson SF, Suchard MA, McCabe ERB and McGhee S. Representational olgionucleotide microarray analysis (ROMA) and comparison of binning and change-point methods of analysis: application to detection of del22q11.2 (DiGeorge) symdrone. Human Mutation, 29, 176-181, 2007.

Seeram NP, Aronson WJ, Zhang Y, Henning SM, Moro A, Lee R, Sartippour M, Harris DM, Rettig MB, Suchard MA, Pantuck AJ, Belldegrun A and Heber D. Pomegranate ellagitannin derived metabolites inhibit prostate cancer growth and localize to the mouse prostate gland. Journal of Agriculture and Food Chemistry, 55, 7732-7737, 2007.

Huelsenbeck JP and Suchard MA. A nonparametric method for accommodating and testing across-site rate variation. Systematic Biology, 56, 975-987, 2007.

Redelings BD and Suchard MA. Incorporating indel information into phylogeny estimation for rapidly emerging pathogens. BMC Evolutionary Biology, 7, 40, 2007.

Minin VN, Dorman KS, Fang F and Suchard MA. Phylogenetic mapping of recombination hotspots in human immunodeficiency virus via spatially smoothed change-point processes. Genetics, 175, 1773-1785, 2007.

Fang F, Ding J, Minin VN, Suchard MA and Dorman KS. cBrother: relaxing parental tree assumptions for Bayesian recombination detection. Bioinformatics, 23, 507-508, 2007.

Liao JC, Mastali M, Li Y, Gau V, Suchard MA, Babbitt J, Gornbein G, Landaw EM, McCabe ERB, Churchill BM and Haake DA. Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. Journal of Molecular Diagnostics, 9, 158-168, 2007.

Guo H, Weiss RE, Gu X and Suchard MA. Time squared: repeated measures on phylogenies. Molecular Biology and Evolution, 24:353-362, 2007.

Kitchen CMR, Lu J, Suchard MA, Hoh R, Martin JN, Kuritzkes DR and Deeks SG. Continued evolution in gp41 after interruption of enfuvirtide in subjects with advanced HIV-1 disease. AIDS Research and Human Retroviruses, 22:1260-1266, 2006.

Seeram NP, Henning SM, Adams LS, Zhang Y, Suchard MA, Li Z and Heber D. Pomegranate juice ellagitannins metabolites are present in human plasma and some persist in urine for up to 48 hours. Journal of Nutrition, 136:2481-2485, 2006.

Suchard MA and Redelings BD. Bali-Phy: simultaneous Bayesian estimation of alignment and phylogeny. Bioinformatics, 22:2047-2048, 2006.

Milane MS, Suchard MA, Wong M-L and Licinio J. Modeling of the temporal patterns of fluoxetine prescriptions and suicide rates in the United States. PLoS Medicine, 3:e190, 2006.

Liao JC, Mastali M, Gau V, Suchard MA, Moeller AK, Bruckner DA, Babbitt JT, Li Y, Gornbein J, Landaw EM, McCabe ERB, Churchill BM and Haake DA. Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. Journal of Clinical Microbiology, 44:561-570, 2006.

Minin VN, Dorman KS, Fang F and Suchard MA. Dual multiple change-point model leads to more accurate recombination detection. Bioinformatics, 21:3034-3042, 2005.

Suchard MA, Weiss RE and Sinsheimer JS. Models for estimating Bayes factors with applications to phylogeny and tests of monophyly. Biometrics, In press.

Suchard MA. Stochastic models for horizontal gene transfer: taking a random walk through tree space. Genetics, 170:419-431, 2005.

Redelings BD and Suchard MA. Joint Bayesian estimation of alignment and phylogeny. Systematic Biology, 2005.

Vongtama R, Lee M, Kim B, Sercarz J, Lin K, Suchard MA, Lee SP, Guillard G. Early nodal response as a predictor for necessity of functional neck dissection, The Cancer Journal, In press.

Kitchen CMR, Philpott S, Burger H, Weiser B, Anastos K and Suchard MA. Evolution of human immunodeficiency virus type 1 coreceptor usage during antiretroviral therapy: a Bayesian approach, Journal of Virology, 78:11296-11302, 2004

Yildiz BO, Suchard MA, Veldhuis JD, Wong M-L, McCann SM and Licino J. Alternations in dynamics of circulating ghrelin, adiponectin and leptin in human obesity, Proceedings of the National Academy of Sciences, USA, 101:10435-10439, 2004.

Haake DA, Suchard MA, Kelley MM, Dundoo M, Alt DP and Zuerner RL. Molecular evolution and mosaicism of leptospiral outer membrane proteins involves horizontal DNA transfer, Journal of Bacteriology, 186:2818-2828, 2004

Suchard JR, Suchard MA and Steinfeldt JL. Physician knowledge of herbal toxicities and adverse drug interactions, European Journal of Emergency Medicine, 11:193-197, 2004.

Sinsheimer JS, Suchard MA, Dorman KS, Fang F and Weiss RE. Are you my mother? Bayesian phylogenetic models to detect recombination among putative parental strains, Applied Bioinformatics 2:131-144, 2003.

Suchard MA, Kitchen CMR, Sinsheimer JS and Weiss RE. Hierarchical phylogenetic models for analyzing multipartite sequence data, Systematic Biology 52:649-664, 2003.

Paraskevis D, Lemey P, Salemi M, Suchard M, Van der Peer Y and Vandamme A. Analysis of the evolutionary relationships of HIV-1 and SIVcpz sequences using Bayesian inference: implications for the origin of HIV-1, Molecular Biology and Evolution 20:1986-1996, 2003.

Suchard MA, Weiss RE, Sinsheimer JS, Dorman KS, Patel M and McCabe ERB. Evolutionary similarity among genes, Journal of the American Statistical Association 98:653-662, 2003.

D'Orsogna MR, Suchard MA and Chou T. Interplay of chemotaxis and chemokinesis mechanisms in bacterial dynamics, Physical Review E 68, 021925, 2003.

Suchard MA, Weiss RE, Dorman KS and Sinsheimer JS. Inferring spatial phylogenetic variation along nucleotide sequences: a multiple change-point model, Journal of the American Statistical Association 98:427-437, 2003.

Suchard MA, Weiss RE and Sinsheimer JS. Testing a molecular clock without an outgroup: derivations of induced priors on branch length restrictions in a Bayesian framework, Systematic Biology 52:48-54, 2003.

Chan JL, Blueher S, Yiannakouris N, Suchard MA, Kratzch J and Mantzoros CS. Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids and leptin: observational and interventional studies in humans. Diabetes 51:2105-2112, 2002.

Suchard MA, Weiss RE, Dorman KS and Sinsheimer JS. Oh brother, where art thou? a Bayes factor test for recombination with uncertain heritage, Systematic Biology 51:715-728, 2002.

Suchard MA, Bailey JN, Elashoff DE and Sinsheimer JS. SNPing Away at candidate genes. Genetic Epidemiology 21:S643-S648, 2001.

Mantzoros CS, Ozata M, Negrao AB, Suchard MA, et al. Synchronicity of frequently sampled TSH and leptin concentrations in healthy adults and leptin deficient subjects: evidence for possible partial TSH regulation by leptin in humans. Journal of Clinical Endocrinology and Metabolism 86:3284-3291, 2001.

Suchard MA, Weiss RE and Sinsheimer JS. Bayesian selection of continuous-time Markov chain evolutionary models, Molecular Biology and Evolution 18:1001-1013, 2001.

Suchard MA. Acromioclavicular and shoulder joints (original artwork), Journal of the American Medical Association 285:2248 and cover (May issue, medical student edition), 2001.

Flechtner-Mors M, Ditschuneit TD, Johnson TD, Suchard MA and Adler G. Metabolic and weight loss effects of long-term dietary intervention in obese patients: four-year results. Obesity Research 8:399-402, 2000.

Chitnavis J, Sinsheimer JS, Suchard MA, Clipsham K and Carr AJ. End-stage coxarthrosis and gonarthrosis: Aetiology, clinical patterns and radiological features of idiopathic osteoarthritis. Rheumatology 39:612-619, 2000.

Bailey JN, Suchard MA, Smalley SL and Sinsheimer JS. Search for a gene by environment interaction: GXE hunt. Genetic Epidemiology 17:S491-S496, 1999.

Suchard MA, Yudkin P and Sinsheimer JS. Are general practitioners willing and able to provide genetic services for common diseases? Journal of Genetic Counseling 8:301-311, 1999.

Suchard MA, Yudkin P, Sinsheimer JS and Fowler G. General practitioners' views on genetic screening for common diseases. British Journal of General Practitioners 49:45-46, 1999.

Deloukas P, et. al. A physical map of 30,000 human genes. Science 282:744-746, 1998.

Suchard MA, Hadfield R, Elliot T and Kennedy S. Beyond providing information: the Internet as a research tool in reproductive medicine. Human Reproduction 13:6-7,1998.

Rose PW and Suchard MA. Taking a family history in primary care is important. British Medical Journal 315:1306, 1997.

Suchard MA, Adamson S and Kennedy S. Piloting patient attitudinal surveys on the web. British Medical Journal 315:529, 1997.

• COPSS Presidents' Award (2013)
• Mitchell Prize (2011)
• John Simon Guggenheim Fellowship (2008)
• Alfred P. Sloan Fellowship (2007)
• Mitchell Prize (2006)
• British Marshall Scholarship (1995)