John II of the Sedre

John entered the Monastery of Ousebuna, between Antioch and Beroea, where he became a monk and studied Greek, Syriac, and theology. He was also at the Monastery of Gubbo Baroyo for a time. John was later appointed secretary to Athanasius I Gammolo, Patriarch of Antioch. Following the conclusion of the Roman-Sasanian War of 602-628, Athanasius dispatched John to the court of the newly enthroned Sasanian emperor Kavadh II at the imperial capital of Ctesiphon. During his return journey, John travelled to the Monastery of St. Matthew in Mesopotamia and invited five bishops and three monks, including Marutha of Tikrit, to accompany him.

John was elected and consecrated Patriarch of Antioch after the death of Athanasius in July 631. His consecration as patriarch was soon followed by the fall of Roman Syria and the Muslim conquest of the Levant. On 9 May 644, John and several bishops were summoned before Emir Umayr ibn Sad al-Ansari of Hims to engage in open debate regarding Christianity and represent the entire Christian community, including non-Syriac Orthodox communities, such as Greek Orthodox Syrians, who are known to have prayed for their safety. The debate was recorded by a certain Severus in the form of a letter and sent to Syriac Orthodox communities to ease discomfort amongst the adherents of the church.

The Emir ,however, was unconvinced by the patriarch and demanded translations of the Gospels into Arabic to confirm John's beliefs, which according to the Chronicle of Michael the Syrian was the first translation of the Gospels into Arabic. John administered the Syriac Orthodox Church until his death in 648 and was buried in the city of Amida.

John is well known for his composition of versified prayers, known as sedres or husoyos, that were integrated into the liturgy and for this reason he is known as "of the Sedre". Nine sedres associated with John correspond to the liturgical calendar whereas three prayers of absolution are to be recited during the consecration of the Eucharist.

As well as this he is known to have written a doctrinal treatise in which he condemns the phantasiast Julianists and also includes the history of the heresy and its leaders. The titles of his works are:

• Letter of the Patriarch Mor Yuhannon concerning His Conversation with the Amir of the Muslims
• Plerophoria, and On Myron
• A Discourse on the Myron
• An Anaphora