John Fowler (by 1520–c. 1575) (died c. 1575), MP
John Fowler (Catholic scholar) (1537–1578/9), Catholic scholar and printer
John Fowler (politician) (1756–1840), U.S. Congressman from Kentucky
Sir John Fowler, 1st Baronet (1817–1898), British railway engineer
John Fowler (agricultural engineer) (1826–1864), English pioneer in the use of steam engines for ploughing
Sir John Fowler (British Army officer) (1864-1939), British Army general
John Edgar Fowler (1866–1930), U.S. Congressman from North Carolina
Jack Fowler (footballer, born 1899) (1899–1975), Plymouth Argyle, Swansea Town and Wales international footballer
Jack Fowler (footballer, born 1902) (1902–1979), English footballer with Bradford City and Torquay United
John Gordon Fowler (1905–1971), USAF general
John Beresford Fowler (1906–1977), British interior designer
John Richard Fowler (1927–2007), local politician in Memphis, Texas
John Fowler (footballer, born 1933) (1933–1976), Scottish footballer with Colchester United
John Fowler (mayor) (born 1954), mayor of the City of South Sydney