F. Eugene Yates

Francis Eugene Yates (February 26, 1927 – January 20, 2015) was an American physiologist and a professor of medicine and medical engineering at University of California Los Angeles.

Eugene Yates was born in Eagle Rock, California. During World War II, Yates was in the U.S. Navy as a medical officer and attended University of Texas (Austin). He attended UCLA from 1945-6. He attended Harvard Medical School from 1946-1950 where he received an MD degree. He served in the Korean War in Guam in 1951-1953 and then went on to Stanford Medical School from 1960-1970.

Yates married Margaret Barnett Yates, MD in 1949. They had five children, Katherine K. Yates, Gregory B. Yates, Peter F. Yates, Eugene B. Yates, and Anna S. Yates.

His death was failure to thrive from a fracture that resulted from having fallen off his exercise bike in Pacific Palisades, California.

Yates worked at Harvard University in the Dept. Physiology from 1953-1960. He was at Stanford Medical School, Physiology Dept. 1960-1970. He was at University of Southern California as the Biomedical Engineering Center Executive Director from 1969-1980. From 1980 to 2001, Yates had a joint appointment at UCLA as Professor of Medicine and Professor of Chemical Engineering. He was the first holder of endowed chair, The Ralph and Marjorie Crump Professorship of Medical Engineering from 1980-1988. In 2002, Yates was the Professor of Geriatric Medical Research, Emeritus at Department of Medicine, UCLA. He retired in 2003.

Yates was a Consulting Principal Scientist at the ALZA Pharmaceutical Company from 1969-1997. He was on the External Advisory Council of NASA-affiliated National Space Biomedical Research Inst. Houston, Texas for 7 years. He worked as a Science Advisor to the John Douglas French Alzheimer’s Foundation in 2003.

He was also a member of Scientific Advisory Board for Dakim, Inc.

Yates coined scientific terms including homeodynamics, pharmacolinguistics, pharmacosemiotics.

Yates’ career has included investigations that have been experimental, clinical, and theoretical in congestive heart failure, hypothalamic-pituitary-adrenal-cortical feedback systems, computer modeling of endocrine and metabolic systems, biology especially in regard to self-organizing systems, aging, temporal organization of living systems, and circadian rhythms.

He served on advisory panels for NIH, NSF, FDA, NASA, and FASEB. Yates was a founding member and past president of the Biomedical Engineering Society. He was on publications committees for the three societies he founded new scientific journals (AJP: Regulatory, Integrative and Comparative Physiology for the American Physiological Society; Annals of Biomedical Engineering for the Biomedical Engineering Society; and Endocrine Reviews for the Endocrine Society).

Yates also organized three major international conferences, one on Self-Organizing Systems in 1979 supported by the Ripple Foundation, AIBS (NAS) in Dubrovnik, Yugoslavia; Nonlinearites in Brain Function in Santa Barbara, California in 1982 supported by the Kroc Foundation; and Chemically-Based Computer Design in 1983 supported by NSF.

• American Physiological Society Living History
• Markle Scholar in Medical Science (Harvard and Stanford),
• Fellow, American Association for the Advancement of Science
• Centennial Scholar of Johns Hopkins University
• Distinguished Service Award by BMES, 2000
• first Upjohn Research Award from the Endocrine Society (with some of his students)
• Stevenson Lecturer at the University of Western Ontario
• Century Forum Scholar at the University of Vermont
• “Celebration Speaker” honoring Paul Dirac's contributions to physics on the occasion of Dirac's 80th birthday.
• Distinguished Lecturer for Indiana University.
• the first lecturer at the University of Connecticut in the endowed series honoring the life and work of Arthur Iberall, entitled “Life and the Sciences of Complexity.”

• Yates, F. Eugene, Lina T. Taskovich, Su I. Yum, and Nieves M. Crisologo. Controlled transdermal administration of melatonin. April 16, 1996. US patent 5508039 

Books

• 1987. Yates, F. Eugene (Ed.), Self-Organizing Systems, The Emergence of Order, New York, Plenum Press, ISBN 978-1-4613-0883-6.
• 2012. Yates, F.E. (Ed.), Self-Organizing Systems, The Emergence of Order. Springer Science & Business Media.

Conference Papers and Technical Reports

• Leeman, S. E., D. W. Glenister and F. E. Yates. Evidence for a central nervous system site of corticosterone inhibition of adrenocorticotrophin (ACTH) release. Fed. Am. Soc. Exp. Biol. Proc. 20:184. 1961.
• Yates, F.E., U.I Richards and N. Keller. Biological activity of protein-bound corticosteroids. Fed. Am. Soc. Exp. Biol. Proc. 22:166, 1963.
• Yates, F.E. Contributions of the liver to steady-state performance and transient responses of the adrenal cortical system. Fed. Am. Soc. Exp. Biol. Proc. 24:723-730, 1964.
• Hedge, G.A. and F.E. Yates. Corticotropin release following injection of lysyl-8-vasopressin (LVP) into rat hypothalamus or adenohypophysis. Fed. Am. Soc. Exp. Biol. Proc. 24:128, 1965.
• Dallman, M.F. and F.E. Yates. Characteristics of corticosteroid inhibition of CRF secretion. Fed. Am. Soc. Exp. Biol. Proc. 26:315, 1967.
• Yates, F.E., and R.D. Brennan. Study of the mammalian adrenal glucocorticoid system by computer simulation. In Conference on Hormonal Control Systems in Health and Disease, IBM Technical Report, pp. 320–3228, 1967.
• Yates, F. E., R. D. Brennan, and J. Urquhart. Application of control systems theory to physiology. Adrenal glucocorticoid control system. Fed. Am. Soc. Exp. Biol. Proc. 28:71-83, 1968.
• Yates, F.E., and R.D. Brennan. Digital simulation of a biochemical control system. In Proc. IBM Scientific Computing Symposium on Computers in Chemistry (320-1954). White Plains, New York. 1969.
• Frohman, L.A., J.W. Maran, F.E. Yates and A.P. Dhariwal. Growth hormone responses to intrapituitary injection of growth hormone releasing factor in rat as measured by radioimmunoassay. Fed. Am. Soc. Exp. Biol. Proc. 30:A198, 1971.
• Yates, F.E. Spectroscopy of metabolic systems. Proc. Ann.. Meet. Soc. Gen. Sys. Res. 24:65, 1980.
• Yates, F.E. Dynamic regulation of mean arterial pressure: special role of renal resistances. Fed. Am. Soc. Exp. Biol. Proc. 42:3143-3149, 1983.
• Bortz, W.M., E.F. Yates, R. Veech and R. Strohman. The Dynamic and Energetic Bases of Health and Aging. NIH Bethesda Md. The Ellison Foundation, 2002

Selected Articles

• Fregly, M. J., F. E. Yates and E. M. Landis. Serum Sodium Concentration of Hypertensive Rats Relation to NaCl Intake, Blood Pressure and Age. Experimental Biol. Medicine 90:695-698, 1955.
• Yates, F.E. and A.B. Pardee. Control of pyrimidine biosynthesis in Escherichia coli by a feedback mechanism. J. Biol. Chem. 221:757, 1956.
• Yates, F. Eugene. Effects of central venous congestion on sodium, potassium and water metabolism in the rat; response to desoxycorticosterone. Am. J. Physiol.--Legacy Content 194: 57-64, 1958.
• Yates, F. E., J. Urquhart and A.L. Herbst. Effects of thyroid hormones on ring A reduction of cortisone by liver. Am. J. Physiol.--Legacy Content 195:373-380, 1958.
• Yates, F. E., J. Urquhart and A.L. Herbst. Impairment of the enzymatic inactivation of adrenal cortical hormones following passive venous congestion of the liver. Am. J. Physiol.--Legacy Content 194: 65-71, 1958.
• Yates, F. E., A.L. Herbst and J. Urquhart. Sex difference in rate of ring a reduction of δ4-3-keto-steroids in vitro by rat liver 1 2. Endocrinology 63:887-902, 1958. http://dx.doi.org/10.1210/endo-63-6-887
• Herbst, A. L., F.E. Yates and D.W. Glenister. Variations in hepatic inactivation of corticosterone with changes in food intake: an explanation of impaired corticosteroid metabolism following noxious stimuli 1 2. Endocrinology 67:222-238, 1960. http://dx.doi.org/10.1210/endo-67-2-222
• Barger, A.C., F.E. Yates and A.M. Rudolph. Renal hemodynamics and sodium excretion in dogs with graded valvular damage, and in congestive failure. Am. J. Physiol.--Legacy Content 200:601-608, 1961.
• Glenister, D.W. and F.E. Yates. Sex difference in the rate of disappearance of corticosterone-4-c14 from plasma of intact rats: further evidence for the influence of hepatic δ4-steroid hydrogenase activity on adrenal cortical function 1. Endocrinology 68:747-758, 1961. http://dx.doi.org/10.1210/endo-68-5-747
• Yates, F.E., S.E. Leeman, D.W. Glenister and M.F. Dallman. Interaction between plasma corticosterone concentration and adrenocorticotropinreleasing stimuli in the rat: evidence for the reset of an endocrine feedback control 1 2. Endocrinology 69:67-80, 1961. http://dx.doi.org/10.1210/endo-69-1-67
• Leeman, S.E., D.W. Glenister and F.E. Yates. Characterization of a calf hypothalamic extract with adrenocorticotropin-releasing properties: evidence for a central nervous system site for corticosteroid inhibition of adrenocorticotropin release. Endocrinology 70:249-262, 1962. http://dx.doi.org/10.1210/endo-70-2-249
• Yates, F.E. and J. Urquhart. Control of plasma concentrations of adrenocortical hormones. Physiol. Rev. 42:359-443, 1962.
• Hedge, G.A., M.B. Yates, R. Marcus and F.E. Yates. Site of Action of Vasopressin in Causing Corticotropin Release 1. Endocrinology 79:328-340, 1966. http://dx.doi.org/10.1210/endo-79-2-328#sthash.tmPraSq4.dpuf
• Kawai, A. and F.E. Yates. Interference with feedback inhibition of adrenocorticotropin release by protein binding of corticosterone. Endocrinology 79:1040-1046, 1966. http://dx.doi.org/10.1210/endo-79-6-1040
• Keller, N., L.R. Sendelbeck, U.I. Richardson, C. Moore and F.E. Yates. Protein Binding of Corticosteroids in Undiluted Rat Plasma 1. Endocrinology 79:884-906, 1966. http://dx.doi.org/10.1210/endo-79-5-884
• Yates, F.E., R. Kirschman and B. Olshen. Analysis of adenohypophysial blood flow in the rat by radioisotope washout: estimate of the vasomotor activity of vasopressin in the anterior pituitary. Endocrinology 79:341-351, 1966. http://dx.doi.org/10.1210/endo-79-2-341
• Dallman, M.F. and F.E. Yates. Anatomical and functional mapping of central neural input and feedback pathways of the adrenocortical system. Proc. Royal Soc. Med. 60:904, 1967.
• Dallman, M.F. and F.E. Yates. Anatomical and functional mapping of central neural input and feedback pathways of the adrenocortical system. Mem. Soc. Endocrinol. 17:39-72, 1968.
• Yates, F.E., R.D. Brennan, J. Urquhart, M.F. Dallman, C.C. Li and W. Halpern. A continuous system model of adrenocortical function. In Systems Theory and Biology, pp. 141–184. Springer Berlin Heidelberg, 1968.
• Dallman, M.F. and F.E. Yates. Dynamic asymmetries in the corticosteroid feedback path and distribution metabolism‐binding elements of the adrenocortical system. Ann. New York Acad. Sci. 156:696-721, 1969. http://dx.doi.org/10.1111/j.1749-6632.1969.tb14008.x
• Dhariwal, A.P.S., S.M. Russell, S.M. McCann and F.E. Yates. Assay of Corticotropin-Releasing Factors by Injection into the Anterior Pituitary of Intact Rats 1. Endocrinol. 84:544-556, 1969. http://dx.doi.org/10.1210/endo-84-3-544
• Keller, N., U.I. Richardson and F.E. Yates. Protein Binding and the Biological Activity of Corticosteroids: In Vivo Induction of Hepatic and Pancreatic Alanine Aminotransferases by Corticosteroids in Normal and Estrogen-Treated Rats 1. Endocrinol. 84:49-62, 1969. http://dx.doi.org/10.1210/endo-84-1-49
• Russell, S.M., A.P.S. Dhariwal, S.M. McCann and F.E. Yates. Inhibition by Dexamethasone of the in Vivo Pituitary Response to Corticotropin-Releasing Factor (CRF) 1. Endocrinol. 85:512-521, 1969. http://dx.doi.org/10.1210/endo-85-3-512
• Yates, F.E. The adrenal glucocorticoid endocrine system: simulation of a biological controller. J. Basic Engineering 91:305-312, 1969. http://dx.doi.org/10.1115/1.3571101
• Brown-Grant, K., R.D. Brennan, and F.E. Yates. Simulation of the Thyroid Hormone-Binding Protein Interactions in Human Plasma 1. J. Clinical Endocrinology & Metabolism 30:733-751, 1970. http://dx.doi.org/10.1210/jcem-30-6-733#sthash.2wRlIX9r.dpuf
• Gonzalez-Luque, A., M. L'age, A.P.S. Dhariwal and F.E. Yates. Stimulation of corticotropin release by corticotropin-releasing factor (CRF) or by vasopressin following intrapituitary infusions in unanesthetized dogs: Inhibition of the responses by dexamethasone 1. Endocrinol. 86:1134-1142, 1970. http://dx.doi.org/10.1210/endo-86-5-1134
• L'age, M., A. Gonzalez-Luque and F.E. Yates. Adrenal blood flow dependence of cortisol secretion rate in unanesthetized dogs. Am. J. Physiol.--Legacy Content 219:281-287, 1970.
• Sendelbeck, L.R. and F.E. Yates. Adrenal cortical and medullary hormones in recovery of tissues from local injury. Am. J. Physiol. -Legacy Content 219:845-853, 1970.
• Yates, F.E., S.M. Russell, M.F. Dallman, G.A. Hedge, S.M. McCann and A.P.S. Dhariwal. Potentiation by vasopressin of corticotropin release induced by corticotropin-releasing factor 1. Endocrinol. 88:3-15, 1971. http://dx.doi.org/10.1210/endo-88-1-3
• Yates, F.E., S.M. Russell and J.W. Maran. Brain-adenohypophysial communication in mammals. Ann. Rev. Physiol. 33:393-444, 1971. http://dx.doi.org/10.1146/annurev.ph.33.030171.002141
• Yates, F.E., D.J. Marsh and A.S. Iberall. Integration of the whole organism: A foundation for a theoretical biology. In: J.A. Behnke (ed.), Challenging Biological Problems: Directions Toward Their Solution. London, Oxford University Press, pp. 110–132, 1972.
• Wei, E., J.W. Maran, A.P.S. Dhariwal and F.E. Yates. Regional responses of the pituitary to corticotropin-releasing factor (CRF) and ammonium ions 1. Endocrinol. 92:710-715, 1973. http://dx.doi.org/10.1210/endo-92-3-710
• Yates, F.E. and A.S. Iberall. Temporal and hierarchical organization in Biosystems. In: J. Urquhart and F.E. Yates (eds.), Temporal Aspects of Therapeutics, N.Y. Plenum Press, pp. 17–34, 1973.
• Bucolo, R.J., R.N. Bergman, D.J. Marsh and F.E. Yates. Dynamics of glucose autoregulation in the isolated, blood-perfused canine liver. Am. J. Physiol.--Legacy Content 227:209-217, 1974.
• Maran, J.W., and F.E. Yates. Locus of ACTH-releasing action of angiotensin II. Endocrinol. 94: A118, 1974.
• Ookhtens, M.D. Marsh, W.W. Smith, R.N. Bergman and F.E. Yates. Fluctuations of plasma glucose and insulin in conscious dogs receiving glucose infusions. Am. J. Physiol. 2226:910, 1974.
• Yates, F.E., and J.W. Maran. Stimulation and inhibition of adrenocorticotropin release. Handbook of Physiology 4, Part 2:367-404, 1974.
• Yates, F.E. and J.W. Maran. The physiology of the mammalian hypothalamo-adenopophysal-adrenal glucocorticoid system-a new hypothesis. Chronobiologia 1:195-223, 1974.
• Yates, F.E., J.W. Maran, G.L. Cryer and D.S. Gann. The pituitary adrenal cortical system: stimulation and inhibition of secretion of corticotrophin. MTP International Review of Science, Physiol. Ser. 1:109-116, 1974.
• Odell Jr, R.H., S.W. Smith and F.E. Yates. A permutation test for periodicities in short, noisy time series. Ann. Biomed. Eng. 3:160-180, 1975. http://dx.doi.org/10.1007/BF02363068
• Yates, F.E. On the mathematical modeling of biological systems: A qualified Physiological adaptation to the environment. Intext Educational Publishers, New York, 1975.
• Yates, F.E., H. Benson, R. Buckles, J. Urquhart, and A. Zaffaroni. Engineering development of therapeutic systems: a new class of dosage forms for the controlled delivery of drugs. Adv. Biomed. Eng. 5:1-34, 1975.
• Miller, R.E., J.W. Maran, G.D. Meier, F.E. Yates and B. Haller. Static gain and dynamics of cortisol secretory response to intravenous corticotropin (ACTH) in unanesthetized dogs analysis by a linear mean-squared estimator. Ann. Biomed. Eng. 4: 364-409, 1976. http://dx.doi.org/10.1007/BF02584526
• Maran, J.W. and F.E. Yates. Cortisol secretion during intrapituitary infusion of angiotensin II in conscious dogs. Am. J. Physiol.-Gastrointestinal and Liver Physiology 233:G273-G285, 1977.
• Smith, S.W., R.H. Odell, D.J. Marsh, and F.E. Yates. Patterns of plasma free fatty acid concentrations in fasted, resting dogs. Am. J. Physiol.-Gastrointestinal and Liver Physiology 232: G25-G34, 1977.
• Yates, F.E. Complexity and the limits of knowledge. Amer. J. Physiol. Reg. Integ. Comp. Physiol. 4:R201, 1978.
• Yates, F.E. Good manners in good modeling: mathematical models and computer simulations of physiological systems. Am. J. Physiol. Reg. Int. Comp. Physiol. 234:R159-R160, 1978.
• Yates, F.E. Osmosis: A transport of confusion. Am. J. Physiol. Reg. Int. Comp. Physiol. 235: R1, 1978.
• Yates, F.E. Thermodynamics and life. Amer. J. Physiol. Reg. Integ. Comp. Physiol. 3:R81, 1978.
• Yates, F.E. Physical biology: A basis for modeling living systems. J. Cyber. Inf. Sci. 2:57, 1979.
• Yates, F.E. Physical causality and brain theories. Am. J. Physiol. Reg. Integ. Comp. Physiol. 7:R277, 1980.
• Yates, F.E., D.J. Marsh, and A.S. Iberall. Integration of the whole organism: A foundation for a theoretical biology. In: J.A. Behnke (ed.), Challenging Biological Problems: Directions Towards Their Solution, New York, Oxford, pp. 110–132, 1980.
• Yates, F.E. Analysis of endocrine signals: The engineering and physics of biochemical communication systems. Biol. Reprod. 24:73, 1981. http://dx.doi.org/10.1095/biolreprod24.1.73
• Yates, F.E. Temporal organization of metabolic processes: A biospectroscopic approach. In: R.N. Bergman and C. Cobelli (eds.) Carbohydrate Metabolism: Quantitative Physiology and Mathematical Modeling. N.Y. Wiley, 1981.
• Yates, F.E. Systems analysis of hormone action. In Biological regulation and development, pp. 25–97. Springer US, 1982.
• Yates, F.E. The 10th JAF Stevenson Memorial Lecture Outline of a physical theory of physiological systems. Can. J. Physiol. Pharmacology 60:217-248, 1982. http://dx.doi.org/10.1139/y82-035
• Yates, F.E. and A.S. Iberall. A skeleton of physical ideas for the dynamics of complex systems. Mathematics and Computers in Simulation 24:430-436, 1982. doi:10.1016/0378-4754(82)90639-5
• Yates, F.E. and P.N. Kugler. Signs, singularities and significance: A physical model for semiotics. Semiotica 52:49, 1982.
• Yates, F.E. Biological similarity: What does Huxley's allometric equation tell us?. Am. J. Physiol. Reg. Int. Comp. Physiol. 244, no. 5 (1983): R589-R590, 1983.
• Yates, F.E. Contribution of statistics to ethics of science. Am. J. Physiol. Reg. Int. Comp. Physiol. 244:R3-R5, 1983.
• Yates, F.E. Systems analysis of hormone action: Principles and strategies. In: R.F. Goldberger and K.R. Yamamoto (eds.). Biological Regulation and Development, Vol. 3A, Plenum Press, N.Y., pp. 25–97, 1984. ISBN 978-1-4757-4619-8
• Yates, F.E. The dynamics of adaptation in living systems. In: Adaptive Control of Ill-Defined Systems, pp. 89–113. Springer US, 1984.
• Kane, R.L., M.E. Kiersch, F.E. Yates, L. Benton, D.H. Solomon, P. Satz and J.C. Beck. Dynamic assessment of cognitive and cardiovascular performance in the elderly. Israel J. Med. Sci. 22: 225-230, 1985.
• Yates, F.E. Semiotics as bridge between information (biology) and dynamics (physics). Rech. Semiot./Semiotic Inquiry 5:347, 1985.
• Yates, F.E. and P.N. Kugler. Similarity principles and intrinsic geometries: contrasting approaches to interspecies scaling. J. Pharmaceutical Sci. 75:1019-1027, 1986. http://dx.doi.org/10.1002/jps.2600751103
• Yates, F.E. and T. Poston. Rate-controlled delivery of endocrine agents: some paradoxical consequences of controlling the inputs. In: H.A.J. Struyker-Boudier (ed.), Principles and Applications of Rate-Controlled Drug Administration and Action. Boca Raton, FL, CRC, 247-272, 1986.
• Benton, L.A., S.J. Berry and F.E. Yates. Ultradian oscillations in human blood pressure: effects of age. In Temporal disorder in human oscillatory systems, pp. 141–149. Springer Berlin Heidelberg, 1987.
• Mayer-Kress, G., F.E. Yates, L. Benton, M. Keidel, W. Tirsch, S.J. Pöppl and K. Geist. Dimensional analysis of nonlinear oscillations in brain, heart, and muscle. Math. Biosci. 90:155-182, 1988. http://dx.doi.org/10.1016/0025-5564(88)90063-6
• Yates, F.E. Evolutionary computing by dynamics in living organisms. In: On Advances in Cognitive Science, pp. 26–49. Am. Assoc. Advance. Sci., 1988.
• Yates, F.E. The evaluation of a ‘co‐operative counselling ’alcohol service which uses family and affected others to reach and influence problem drinkers. Brit. J. Addiction 83:1309-1319, 1988. http://dx.doi.org/10.1111/j.1360-0443.1988.tb03042.x
• Benton, L.A., S.J. Berry and F.E. Yates. Ultradian rhythmic models of blood pressure variation in normal human daily life. Chronobiologia 17:95-116, 1989.
• Benton, L.A. and F.E. Yates. Ultradian adrenocortical and circulatory oscillations in conscious dogs. Am. J. Physiol. Reg. Int. Comp. Physiol. 258:R578-R590, 1990.
• Place, V.A., L. Atkinson, D.A. Prather, N. Trunnell and F.E.Yates. Transdermal testosterone replacement through genital skin. In Testosterone, pp. 165–181. Springer Berlin Heidelberg, 1990.
• Yates, F.E., and L.A. Benton. Blood pressure levels and variance assessed by ambulatory monitoring: optimal parameters. Ann. Biomed. Eng. 18:377-405, 1990. http://dx.doi.org/10.1007/BF02364156
• Yates, F.E. Aging as prolonged morphogenesis: a topological sorcerer’s apprentice. Metaphors of aging in science and the humanities. New York: Springer, pp. 199–218, 1991.
• Yates, F.E. Pharmacosemiotics: Where is the message in the drug. In: B.E. Litowitz and P.S. Epstein (eds.), Semiotic Perspectives on Clinical Theory and Practice Medicine, Neuropsychiatry and Psychoanalysis, pp. 65–79, 1991.
• Yates, F.E. and L.A. Benton. Characteristics of ultradian and circadian rhythms of selected cardiovascular variablesa. Ann. New York Acad. Sci. 618:38-56, 1991. http://dx.doi.org/10.1111/j.1749-6632.1991.tb27236.x
• Yates, F.E. Fractal applications in biology: Scaling time in biochemical networks. Methods in Enzymology 210:636-675, 1992. http://dx.doi.org/10.1016/0076-6879(92)10032-9
• Yates, F.E. Order and complexity in dynamical systems: Homeodynamics as general mechanism for biology. In: D.C. Mikulecky and M. Witten (eds.), Dynamics and Thermodynamics of Complex Systems, Pergamon, N.Y., 1992.
• Yates, F.E. On frailty: When being no longer implies becoming, JAGS, 41:1009-1010, 1993.
• Yates, F.E. The logic of life, Self-organizing systems, In: C.A.R. Boyd and D. Noble (eds.). The Logic of Life: The Challenge of Integrative Physiology. Oxford University Press, N.Y., pp. 189–218, 1993.
• Yates, F.E., L.A. Benton and J.C. Beck. Risk assessment and early detection of functional declines. Aging, health and competence. Amsterdam: Elsevier, pp. 87–107, 1993.
• Yates, F.E., Order and complexity in dynamical systems: Homeodynamics and a generalized mechanics for biology. Math. Computer Model, 19:49, 1994. http://dx.doi.org/10.1016/0895-7177(94)90189-9
• Yates, F.E. The therapeutic application of a computer problem-solving program to teach coping strategies to problem drinkers. New Tech. Human Services 7:15-21, 1994.
• Yates, F.E. and L.A. Benton. Biological senescence: Loss of integration and resilience. Can. J. Aging/La Revue Canadienne du Vieillissement 14:106-120, 1995. http://dx.doi.org/10.1017/S0714980800010552
• Yates, F.E. and L.A. Benton. Loss of integration and resiliency with age: a dissipative destruction. Comprehensive Physiol., 1995. http://dx.doi.org/10.1002/cphy.cp110122
• Shannahoff-Khalsa, D.S., B. Kennedy, F.E. Yates and M.G. Ziegler. Ultradian rhythms of autonomic, cardiovascular, and neuroendocrine systems are related in humans. Am. J. Physiol. Reg. Int. Comp. Physiol. 270:R873-R887, 1996.
• Yates, F.E. Homeostasis. In: J. Birren (ed.), Encyclopedia of Gerontology. New York, Academic pp. 679–686, 1996.
• Yates, F.E. Theory of aging: Biological. In: J. Birren (ed.), Encyclopedia of Gerontology. New York, Academic, pp. 545–555, 1996.
• Shannahoff-Khalsa, D.S., B. Kennedy, F.E. Yates and M.G. Ziegler. Low-frequency ultradian insulin rhythms are coupled to cardiovascular, autonomic, and neuroendocrine rhythms. Am. J. Physiol. Reg. Int. Comp. Physiol. 272:R962-R968, 1997.
• Yates, F.E. Microsemiosis. Semiotics: A Handbook on the Sign-Theoretic Foundations of Nature and Culture 1:457-464, 1997.
• Shannahoff-khalsa, D.S. and F.E. Yates. Ultradian sleep rhythms of lateral EEG, autonomic, and cardiovascular activity are coupled in humans. Int. J. Neuroscience 101:21-43, 2000. http://dx.doi.org/10.3109/00207450008986490
• Sehl, M.E. and F.E. Yates. Kinetics of human aging I. Rates of senescence between ages 30 and 70 years in healthy people. J. Gerontology Ser. A: Biological Sciences and Medical Sciences 56:B198-B208, 2001. http://dx.doi.org/10.1093/gerona/56.5.B198
• Shannahoff-Khalsa, D.S., J.C. Gillin, F.E.Yates, A. Schlosser and E.M. Zawadzki. Ultradian rhythms of alternating cerebral hemispheric EEG dominance are coupled to rapid eye movement and non-rapid eye movement stage 4 sleep in humans. Sleep Medicine 2:333-346, 2001. http://dx.doi.org/10.1016/S1389-9457(00)00066-6
• Yates, F.E. Complexity of a human being: Changes with age. Neurobiol. Aging, 23:17-9, 2002.
• Yates, F.E. On the maturation of mathematical modeling of endocrine systems. Am. J. Physiol. Reg. Int. Comp. Physiol. 285:R932, 2003. http://dx.doi.org/10.1152/ajpregu.00348.2003
• Yates, F.E. Three views of translations. In: S. Petrilli (ed.), Translation, Translation. Rodopi, N.Y., p. 29-306, 2003.
• Yates, F.E. Homeokinetics/Homeodynamics: A physical heuristic for life and complexity. Ecol. Psych. 20:148, 2008. http://dx.doi.org/10.1080/10407410801977546
• Yates, F.E. Modeling frailty: Can a simple feedback model suffice? Mech. Ageing Dev. 129:671-2, 2008. http://dx.doi.org/10.1016/j.mad.2008.09.015.
• Yates, F.E. and L.B. Yates. Ultradian rhythms as the dynamic signature of life. In: Ultradian Rhythms from Molecules to Mind, pp. 249–260. Springer Netherlands, 2008.
• Yates, F.E. On varieties of information. Ecol. Psych. 3:185, 2012.