Alexander Tropsha

Alexander Tropsha is a chemist and professor at the UNC Eshelman School of Pharmacy. Tropsha is Associate Dean for Pharmacoinformatics and Data Science as well as an Adjunct Professor in the Biomedical Engineering and Computer Science Departments. His principal research interest is quantitative structure-activity (QSAR) and structure-property relationships.

In 1982, Tropsha earned his master's degree chemistry from Moscow State University. Tropsha continued his studies under Lev S. Yaguzhinski earning his PhD in biochemistry and pharmacology in 1986.

Tropsha immigrated to the US in 1989 where he began his career in academics as an assistant professor director of the Laboratory for Molecular Modeling at the University of North Carolina at Chapel Hill in 1991. Tropsha became a professor in 2004 and in 2008 he became the K.H. Lee Distinguished Professor at Eshelman.

Research in his laboratory includes the development and application of k-nearest neighbor pattern recognition methods to the field of QSARs and application of the Delaunay tessellation technique to protein structure analysis. His recent work focuses on methods of rigorous validation of QSAR models and the development of best-practice QSAR workflows.