William, Will, Bill or Billy Lee may refer to:
Business
- William F. Lee, co-managing partner of law firm WilmerHale
- William Ellsworth Lee (1867–1936), American oil businessman and financier
- William States Lee III (1929–1996), ex-chairman of the board of Duke Power
Arts, entertainment and literature
- William Harold Lee (1884–1971), American theater designer and architect
- Will Lee (1908–1982), American actor and comedian
- Bill Lee (singer) (1916–1980), American singer who voiced many Disney characters
- Bill Lee (musician) (born 1928), American jazz musician and composer
- Billy Lee (actor) (1929–1989), American child actor
- Will Lee (bassist) (born 1952), aka William Franklin Lee IV, American musician and bassist
- Bill Lee (author) (born 1954), Chinese-American writer and ex-gang member
- Will Yun Lee (born 1971), American actor
- William Gregory Lee (born 1973), American actor
- William Poy Lee (born 1951), author and political activist
- William Franklin Lee III (1929–2011), pianist, former Dean of the University of Miami School of Music
- William Lee (civil engineer) (1812–1891), English bibliographer of Daniel Defoe
- William Lee (captain), colonial writer and ship's captain
- William Lee, pen name used frequently by the late Beat Generation writer William S. Burroughs when writing his work
- William Lee (2013-?), Australian actor
Politics, law, and government
- William Lee (Australian politician) (1794–1870), New South Wales politician
- William Lee (diplomat) (1739–1795), American diplomat
- William Lee (1801–1881), British Member of Parliament for Maidstone, 1853–1857 and 1859–1870
- William H. Lee (New York) (1876–1954), New York state senator
- William Henry Lee (1799–1878), Canadian clerk of the Privy Council
- William Henry Fitzhugh Lee (1837–1891), Confederate Army general and US congressman
- William Little Lee (1821–1857), first Chief Justice of the Supreme Court for the Kingdom of Hawaii
- William Swain Lee (born 1935), American lawyer and politician
- William E. Lee (1852–1920), Minnesota politician
- William Scott Lee (1851–1916), mayor of Denver, Colorado, 1887–1889
- William Lee (English judge) (1688–1754), British judge and MP for Wycombe
- William Charles Lee (born 1938), U.S. federal judge
- Bill Lee (Georgia politician) (1925–2014), American politician from the state of Georgia
- Bill Lann Lee (born 1949), Chinese-American civil rights lawyer
- William Henry Lee (1799–1878), Canadian civil servant
Sports
- Bill Lee (American football) (1911–1998), American football player
- Bill Lee (left-handed pitcher) (born 1946), American baseball pitcher [aka Spaceman]
- Bill Lee (right-handed pitcher) (1909–1977), American baseball pitcher
- Bill Lee (yacht designer) (born 1942), designer of Merlin 70' Santa Cruz ULDB
- Billy Lee (baseball) (1894–1984), American baseball outfielder
- Billy Lee (footballer) (1878–1934), English footballer
- William "Caveman" Lee (born 1956), American middleweight boxer
Religion
- William Lee (bishop of Clifton) (1875–1948), Roman Catholic bishop
- William Lee (bishop of Waterford and Lismore) (born 1941), Roman Catholic bishop
Military
- William C. Lee (1895–1948), American Army soldier and general
- William Raymond Lee (1807–1891), Confederate soldier
Fiction
- Billy Lee, character in video game series Double Dragon
- Bill Lee (Stargate), fictional character in the television series Stargate SG-1 and Stargate Atlantis
- Willy Lee (Cocaine Blues), fictional murderer