James Reynolds may refer to:
- James Reynolds (actor) (born 1946), American actor
- James Reynolds (composer) (born 1953), American composer of music for radio plays, theatre and opera
- James Reynolds (correspondent) (born 1974), correspondent for the BBC
- James Reynolds (cricketer) (1866–1950), English cricketer
- James Reynolds (judge) (1684–1747), Chief Justice of the Irish Common Pleas
- James Reynolds (1686-1739), British Member of Parliament for Bury St Edmunds, 1717–25
- James Reynolds (sailor), American sailor in the Star class
- Sir James Reynolds, 1st Baronet (1865–1932), British Conservative party politician
- James B. Reynolds (1779–1851), U.S. Representative from Tennessee
- James Burton Reynolds (1870–1948), Assistant Secretary of the Treasury where he was accused of taking bribes from the Sugar Trust
- James C. Reynolds, Wisconsin State Senator
- James F. Reynolds (1919–2003), American businessman; commercial cable TV pioneer
- James F. Reynolds (mixer), music producer, mix engineer and musician
- James Henry Reynolds (1844–1932), Irish Victoria Cross recipient
- James J. Reynolds (1907–1986), Undersecretary of Labor to US President Lyndon Johnson
- James M. Reynolds (1830–?), American pioneer and politician
- James Reynolds, husband of Maria Reynolds