Fatal may refer to:
Causing to die
Mass media
- Fatal (album), an album by Hussein Fatal
- Fatal Recordings, a feminist record label
- Fatal (film), a 2010 French film starring Stéphane Rousseau
- Fatal, a rapper who collaborated with the band Therapy? on the song "Come and Die" from the Judgment Night film soundtrack
- "Fatal", a song by Pearl Jam from Lost Dogs
- Fatal Fury, 2D fighting game series by SNK
- "Fatal" a bonus track by Motionless In White from the album "Infamous".