Charles Lewis may refer to:
Athlete
Politicians
- Charles Lewis (New Zealand politician) (1857–1927), New Zealand politician
- Charles G. Lewis (1823–?), American politician in Wisconsin
- Charles H. Lewis (1871–1965), American politician in Ohio
- Charles Hance Lewis (1816–?), American diplomat from Virginia, United States Ambassador to Portugal, 1870–1875
- Charles L. Lewis (California politician) (1966–2004), San Diego city council member
- Charles Lundy Lewis (1852–1936), American judge, justice of the Minnesota Supreme Court
- Charles S. Lewis (1821–1878), U.S. Representative from Virginia
- Sir Charles Lewis, 1st Baronet (1825–1893), Member of Parliament for Londonderry City, 1872–1886, and North Antrim, 1887–1892
- Jerry Lewis (California politician) (Charles Jeremy Lewis, born 1934), U.S. Representative from California
Military
- Charles Lewis (soldier) (1733–1774), Virginian colonel killed in the Battle of Point Pleasant, namesake of Lewis County, West Virginia
- Charles Algernon Lewis (1807–1904), British Army officer
Artists
Other