Andrés Rodríguez is the name of:
- Andrés Rodríguez (politician) (1923–1997), president of Paraguay
- Andrés Rodríguez (basketball) (born 1981), basketball player from Puerto Rico
- Andrés Rodríguez (chess player), chess grandmaster from Uruguay, in FIDE World Chess Championship 1999
- Andrés Rodríguez (cyclist), Colombian road cyclist in the Colombian National Time Trial Championships
- Andres Rodriguez (show jumper) (1984–2016), Venezuelan showjumper
- Andrés Rodríguez (athlete) (born 1985), Panamanian sprinter